Biochemistry – Definition and History
What is Biochemistry?
The term Biochemistry was first introduced by. German scientist / chemist CARL NEUBERG in 1903
Definition of Biochemistry:
Biochemistry may be defined as a science concerned with chemical nature and chemical behaviour of the living matter. Biochemistry may be treated as a discipline in which biological phenomenon are analyzed in terms of chemistry. Hence termed as biological chemistry or Chemical Biology
History of Biochemistry
In terms of history biochemistry is a young science.
Name of Scientist
Karl Wilhelm Scheele
Isolated citric acid, lactic acid, malic acid
Father of biochemistry, developed the concept of oxidation of organic materials
Suggested the name proteins
Identified organises responsible for fermentation.
Studied structure of carbohydrates, Amino acids and fats.
F. G. Hopkins
Concept of deficiency diseases
Isolated and characterized the curative agent for scurvy (Vitamin C), rickets (Vit. -D D), Beriberi (Vit-B1)
Watson and Crick
Helical model of mucleic acid
First crystallized enzyme crease, Father of modem enzymology
Discovery of the first essential amino acid threonine.
Formulation of sugars as Pyranose form OR Furanose form
Biochemistry deals with study of
1. The nature of the chemical constituents of the living matter and the chemical substances produced by living things.
2. The functions and transformations of their chemical entities in biological systems.
3. The chemical and energetic changes associated with the transformation in the course of the activity of living matter.